Molecular analysis of highly pathogenic avian influenza virus of subtype H5N1 isolated from wild birds and mammals in northern Germany.
Identifieur interne : 000456 ( Main/Exploration ); précédent : 000455; suivant : 000457Molecular analysis of highly pathogenic avian influenza virus of subtype H5N1 isolated from wild birds and mammals in northern Germany.
Auteurs : Siegfried Weber [Allemagne] ; Timm Harder ; Elke Starick ; Martin Beer ; Ortrud Werner ; Bernd Hoffmann ; Thomas C. Mettenleiter ; Egbert MundtSource :
- The Journal of general virology [ 0022-1317 ] ; 2007.
Descripteurs français
- KwdFr :
- Allemagne (épidémiologie), Analyse de séquence d'ADN, Animaux, Animaux sauvages (virologie), Anseriformes (virologie), Chats, Données de séquences moléculaires, Flambées de maladies, Glycoprotéine hémagglutinine du virus influenza (génétique), Grippe chez les oiseaux (virologie), Humains, Infections à Orthomyxoviridae (médecine vétérinaire), Infections à Orthomyxoviridae (virologie), Infections à Orthomyxoviridae (épidémiologie), Maladies des chats (virologie), Maladies des chats (épidémiologie), Phylogénie, Sialidase (génétique), Sous-type H5N1 du virus de la grippe A (), Sous-type H5N1 du virus de la grippe A (génétique), Sous-type H5N1 du virus de la grippe A (isolement et purification), Sous-type H5N1 du virus de la grippe A (pathogénicité), Substitution d'acide aminé, Séquence d'acides aminés.
- MESH :
- génétique : Glycoprotéine hémagglutinine du virus influenza, Sialidase, Sous-type H5N1 du virus de la grippe A.
- isolement et purification : Sous-type H5N1 du virus de la grippe A.
- médecine vétérinaire : Infections à Orthomyxoviridae.
- pathogénicité : Sous-type H5N1 du virus de la grippe A.
- virologie : Animaux sauvages, Anseriformes, Grippe chez les oiseaux, Infections à Orthomyxoviridae, Maladies des chats.
- épidémiologie : Allemagne, Infections à Orthomyxoviridae, Maladies des chats.
- Analyse de séquence d'ADN, Animaux, Chats, Données de séquences moléculaires, Flambées de maladies, Humains, Phylogénie, Sous-type H5N1 du virus de la grippe A, Substitution d'acide aminé, Séquence d'acides aminés.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Amino Acid Sequence, Amino Acid Substitution, Animals, Animals, Wild (virology), Anseriformes (virology), Cat Diseases (epidemiology), Cat Diseases (virology), Cats, Disease Outbreaks, Germany (epidemiology), Hemagglutinin Glycoproteins, Influenza Virus (genetics), Humans, Influenza A Virus, H5N1 Subtype (classification), Influenza A Virus, H5N1 Subtype (genetics), Influenza A Virus, H5N1 Subtype (isolation & purification), Influenza A Virus, H5N1 Subtype (pathogenicity), Influenza in Birds (virology), Molecular Sequence Data, Neuraminidase (genetics), Orthomyxoviridae Infections (epidemiology), Orthomyxoviridae Infections (veterinary), Orthomyxoviridae Infections (virology), Phylogeny, Sequence Analysis, DNA.
- MESH :
- chemical , genetics : Hemagglutinin Glycoproteins, Influenza Virus, Neuraminidase.
- geographic , epidemiology : Germany.
- classification : Influenza A Virus, H5N1 Subtype.
- epidemiology : Cat Diseases, Orthomyxoviridae Infections.
- genetics : Influenza A Virus, H5N1 Subtype.
- isolation & purification : Influenza A Virus, H5N1 Subtype.
- pathogenicity : Influenza A Virus, H5N1 Subtype.
- veterinary : Orthomyxoviridae Infections.
- virology : Animals, Wild, Anseriformes, Cat Diseases, Influenza in Birds, Orthomyxoviridae Infections.
- Amino Acid Sequence, Amino Acid Substitution, Animals, Cats, Disease Outbreaks, Humans, Molecular Sequence Data, Phylogeny, Sequence Analysis, DNA.
Abstract
Analysis of the full-length sequences of all eight segments of the German wild-bird H5N1 highly pathogenic avian influenza virus index isolate, A/Cygnus cygnus/Germany/R65/2006, and an H5N1 isolate from a cat (A/cat/Germany/R606/2006) obtained during an outbreak in February 2006 revealed a very high similarity between these two sequences. One amino acid substitution in the PA gene, encoding a protein involved in virus RNA replication, and one amino acid substitution in the haemagglutinin (HA) protein were observed. Phylogenetic analyses of the HA and neuraminidase nucleotide sequences showed that avian influenza H5N1 isolates from the Astrakhan region located in southern Russia were the closest relatives. Reassortment events could be excluded in comparison with other 'Qinghai-like' H5N1 viruses. In addition, an H5N1 isolate originating from a single outbreak in poultry in Germany was found to be related closely to the H5N1 viruses circulating at that time in the wild-bird population.
DOI: 10.1099/vir.0.82300-0
PubMed: 17251574
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Outbreaks</term><term>Humans</term><term>Molecular Sequence Data</term><term>Phylogeny</term><term>Sequence Analysis, DNA</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de séquence d'ADN</term><term>Animaux</term><term>Chats</term><term>Données de séquences moléculaires</term><term>Flambées de maladies</term><term>Humains</term><term>Phylogénie</term><term>Sous-type H5N1 du virus de la grippe A</term><term>Substitution d'acide aminé</term><term>Séquence d'acides aminés</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Allemagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Analysis of the full-length sequences of all eight segments of the German wild-bird H5N1 highly pathogenic avian influenza virus index isolate, A/Cygnus cygnus/Germany/R65/2006, and an H5N1 isolate from a cat (A/cat/Germany/R606/2006) obtained during an outbreak in February 2006 revealed a very high similarity between these two sequences. One amino acid substitution in the PA gene, encoding a protein involved in virus RNA replication, and one amino acid substitution in the haemagglutinin (HA) protein were observed. Phylogenetic analyses of the HA and neuraminidase nucleotide sequences showed that avian influenza H5N1 isolates from the Astrakhan region located in southern Russia were the closest relatives. Reassortment events could be excluded in comparison with other 'Qinghai-like' H5N1 viruses. In addition, an H5N1 isolate originating from a single outbreak in poultry in Germany was found to be related closely to the H5N1 viruses circulating at that time in the wild-bird population.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">17251574</PMID><DateCompleted><Year>2007</Year><Month>03</Month><Day>15</Day></DateCompleted><DateRevised><Year>2007</Year><Month>01</Month><Day>25</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-1317</ISSN><JournalIssue CitedMedium="Print"><Volume>88</Volume><Issue>Pt 2</Issue><PubDate><Year>2007</Year><Month>Feb</Month></PubDate></JournalIssue><Title>The Journal of general virology</Title><ISOAbbreviation>J. Gen. Virol.</ISOAbbreviation></Journal><ArticleTitle>Molecular analysis of highly pathogenic avian influenza virus of subtype H5N1 isolated from wild birds and mammals in northern Germany.</ArticleTitle><Pagination><MedlinePgn>554-8</MedlinePgn></Pagination><Abstract><AbstractText>Analysis of the full-length sequences of all eight segments of the German wild-bird H5N1 highly pathogenic avian influenza virus index isolate, A/Cygnus cygnus/Germany/R65/2006, and an H5N1 isolate from a cat (A/cat/Germany/R606/2006) obtained during an outbreak in February 2006 revealed a very high similarity between these two sequences. One amino acid substitution in the PA gene, encoding a protein involved in virus RNA replication, and one amino acid substitution in the haemagglutinin (HA) protein were observed. Phylogenetic analyses of the HA and neuraminidase nucleotide sequences showed that avian influenza H5N1 isolates from the Astrakhan region located in southern Russia were the closest relatives. Reassortment events could be excluded in comparison with other 'Qinghai-like' H5N1 viruses. In addition, an H5N1 isolate originating from a single outbreak in poultry in Germany was found to be related closely to the H5N1 viruses circulating at that time in the wild-bird population.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Weber</LastName><ForeName>Siegfried</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institute of Molecular Biology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harder</LastName><ForeName>Timm</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Starick</LastName><ForeName>Elke</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Beer</LastName><ForeName>Martin</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Werner</LastName><ForeName>Ortrud</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Hoffmann</LastName><ForeName>Bernd</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Mettenleiter</LastName><ForeName>Thomas C</ForeName><Initials>TC</Initials></Author><Author ValidYN="Y"><LastName>Mundt</LastName><ForeName>Egbert</ForeName><Initials>E</Initials></Author></AuthorList><Language>eng</Language><DataBankList 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UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Gen Virol</MedlineTA><NlmUniqueID>0077340</NlmUniqueID><ISSNLinking>0022-1317</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019267">Hemagglutinin Glycoproteins, Influenza Virus</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.2.1.18</RegistryNumber><NameOfSubstance UI="D009439">Neuraminidase</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000595" MajorTopicYN="N">Amino Acid Sequence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019943" MajorTopicYN="N">Amino Acid Substitution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000835" MajorTopicYN="N">Animals, Wild</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D046090" MajorTopicYN="N">Anseriformes</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002371" MajorTopicYN="N">Cat Diseases</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002415" MajorTopicYN="N">Cats</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019267" MajorTopicYN="N">Hemagglutinin Glycoproteins, Influenza Virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053124" MajorTopicYN="N">Influenza A Virus, H5N1 Subtype</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005585" MajorTopicYN="N">Influenza in Birds</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009439" MajorTopicYN="N">Neuraminidase</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009976" MajorTopicYN="N">Orthomyxoviridae Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017422" MajorTopicYN="Y">Sequence Analysis, DNA</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>1</Month><Day>26</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>3</Month><Day>16</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>1</Month><Day>26</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">17251574</ArticleId><ArticleId IdType="pii">88/2/554</ArticleId><ArticleId IdType="doi">10.1099/vir.0.82300-0</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country></list><tree><noCountry><name sortKey="Beer, Martin" sort="Beer, Martin" uniqKey="Beer M" first="Martin" last="Beer">Martin Beer</name><name sortKey="Harder, Timm" sort="Harder, Timm" uniqKey="Harder T" first="Timm" last="Harder">Timm Harder</name><name sortKey="Hoffmann, Bernd" sort="Hoffmann, Bernd" uniqKey="Hoffmann B" first="Bernd" last="Hoffmann">Bernd Hoffmann</name><name sortKey="Mettenleiter, Thomas C" sort="Mettenleiter, Thomas C" uniqKey="Mettenleiter T" first="Thomas C" last="Mettenleiter">Thomas C. Mettenleiter</name><name sortKey="Mundt, Egbert" sort="Mundt, Egbert" uniqKey="Mundt E" first="Egbert" last="Mundt">Egbert Mundt</name><name sortKey="Starick, Elke" sort="Starick, Elke" uniqKey="Starick E" first="Elke" last="Starick">Elke Starick</name><name sortKey="Werner, Ortrud" sort="Werner, Ortrud" uniqKey="Werner O" first="Ortrud" last="Werner">Ortrud Werner</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Weber, Siegfried" sort="Weber, Siegfried" uniqKey="Weber S" first="Siegfried" last="Weber">Siegfried Weber</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:17251574" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a GrippeAllemagneV3
| This area was generated with Dilib version V0.6.35. |  |